Showing posts with label Bravelle. Show all posts
Showing posts with label Bravelle. Show all posts

Monday, November 7, 2011

CD 10 {Hail Mary Cycle}

I went in for my first monitoring appointment with Mr. Wandy today and this cycle is already turning out to be different. First of all, my right ovary is dead. Once again, I didn't produce any sizable follicles on that side even though we started out with a higher dose in hopes to kick start both ovaries. My RE thinks that's just they way my body is now, and the only way to wake it up would be to give me much higher doses of stims. But with IUI's, that's not really an option with out having a VERY high risk for multiples, so high that that's out of the question. So lefty is just going to have to pull all the weight around here!

I had 3 follies on the left side, a 20mm, a 16mm, and a 15mm. My lining was better than the previous cycles at a 8.5. I cant believe I was pretty much ready to go on CD 10. This is the response that I used to get! These last 2 cycles I was using Bravelle because a dear friend gave it to me (and lets be honest, fertility drugs are MUCHO expensive) and I just wasnt getting great results. Bottom line, what I've learned is that I have a MUCH better response on follistim than I do with Bravelle!

I will do one more 75iu follisitm shot tonight, trigger shot tomorrow night at 11:30pm, and go in for my insemination on Thursday at 9:30 am! Now I just have to keep everything crossed that we have a semi decent sperm count after the thaw on Thursday.

My RE seemed VERY optimistic and thinks I responded beautifully. And for the first time in many cycles, I walked out feeling great. Great about my appointment, great about this cycle, and great about the future!

Wednesday, July 20, 2011

Our Hail Mary Cycle

It's official. We are starting our final treatment cycle. This is it folks! It's our hail mary-please-god-let-it-work-or-we-will-never-have-another-baby cycle. I called into my clinic on Monday (CD 1) only to find out that my RE was on vacation. My plan was to have my CD 3 scan scheduled with my RE so we could also discuss protocol changes. Sort of a two for the price of appointment. Well once I found out he wasn't there, I told the nurse what I had in mind for this next cycle. All injects and NO clomid because of the headaches. It was so bad last cycle that I swore I would NEVER TAKE THAT DRUG AGAIN. I would rather take the shots every single day than deal with those headaches.

She said she would talk to the other RE and see if he was willing to go along with it. I wasn't so sure he'd be okay with it based off looking at my chart...I mean they are pretty conservative and given my age (28/29 next month) and the fact that I have had 2 successful pregnancies, and at my RE himself has twins, they are VERY CAREFUL with me. I get it. I don't want HOM, or even twins either, but lets loosen up the reins here a bit. The last 2 haven't worked and this is my last shot. We are using frozen sperm, so LETS DO IT! I wanna go out with a bang!

After waiting patiently for the call to get the go ahead or not, I was very surprised when they called me back and told me that they called MY RE on vacation to go over my med protocol. See? This is why I love them! They all know SO much is riding on this. They are all really rooting for me, and I just love them.

Well he went along with it! A very conservative injectable dose, but he went along with it! I start the shots today! My protocol is as follows (I will be using Bravelle again):

CD 3 : 100 units
CD 4, 6, & 8, : 75 units

Start OPK's on CD 8 (man those are the devil) and come in for monitoring on CD 11.

I started doing some reading and it seems like when people are on only injects, they start monitoring much sooner than CD 11. For those of you who have done inject IUI's- should I be worried? Do you think they should bring me in sooner? As you can see it is a very conservative dose, but I know the injects really speed things along and you can go a lot sooner.

I have never done all injects before so I am VERY interested to see how things go this time! Hoping for 3-4 nice mature follies. Follie dust please :) Lets get these eggies growing!

Saturday, July 2, 2011

CD 11

Today was my first follie check and I was eager to get in because I haven't been feeling much going on in my ovaries. Usually, I feel twinges, fullness, tenderness, and bloating, All signs that something is cooking in there. This cycle, none of that despite the increase to 100mg of clomid and 3 shots of bravelle. So I was really anxious to see what I had going on.

Well I can say that I am already extremely discouraged with the cycle and I haven't even had my IUI yet. I just want my last cycle to be PERFECT and in my mind that is 3-4 nice 18mm-20mm follies and a nice thick lining and ready to go on CD 11.

Today I had a 25mm (too big?) and a 15mm on the left, and a 19mm on the right. Lining was 7. They like it to be between 7-11, so it is within that range although the lowest. I usually have a lining of at least 9.

I don't know. I just already feel like this is going to fail. I think the biggest follie is too big and really a cyst- even though the nurse insisted it wasn't. I think that the 15 can go either way, so I cant totally count that. Although it should be closer to mature by Monday. I just a wanted a few more nice targets since we are using such bad sperm. IDK, I just wanted more ideal scenario given our circumstances....

Also, the sperm guy suggested we only defrost 4 vials. He said that he didn't see the benefit of using more than that. I wasn't expecting that either. I've always thought that we would use the rest of the 9 vials with this last shot, but according to him it wouldn't increase my chances to use more than 4. Another IDK...

So I will trigger tonight at 10:30pm. We will use 4 vials per his recommendations for our IUI on Monday morning, which leaves me with 5 vials left. Good I guess because that means if this doesn't work I have 1 more attempt. A bonus since I was not expecting that but I really don't understand his logic.

I really am not feeling good about this. I know I should try and be more positive, but so much is riding on this that I just wanted it to be perfect. I would feel SO much better if it were a better looking cycle in my mind. I am just feeling so discouraged :( I hate this.

Thursday, June 23, 2011

Back on The Wagon

The fertility treatment wagon that is! Today is CD 2 and I will start meds tomorrow for our very last cycle. My RE changed my protocol a little this cycle as as result of what happened last cycle.

CD 3-7 100 mg Clomid

CD 5 & 8 a 75 unit shot of Bravelle

Start OPK's on CD 8

First monitoring appointment on CD 11- which is Saturday July 2 and we'll go from there.

If you remember last cycle I started out great, but then things started getting weird and I stalled out mid cycle, Because of this my RE said that he decided to up my clomid. He said it can help the follicles mature later in the cycle, and that's when I started having problems last cycle. He also switched my injection days, to only 5 & 8, not sure why but my RE is very conservative and I think he is scared that I will over produce.

Here's another thing, my actual RE will be out of town while I am cycling this time. I am very nervous about this. He knows my situation and we have very open communication with one another, so if things go array again we will be consulting with another Dr. in the practice. I mean, that's fine but this cycle is critical. It is our LAST SHOT and I just really wish my Dr was there. The nurse said she was going to ask if he will be available by phone in case we need him, and hopefully he will be. It makes me a little nervous, but I know I am still in good hands with the other RE's. One of them I've seen a couple times, he actually did both my HSG's.

You may also notice that I switched from follistim to bravelle. Well that's because the follistim I was using was left over from when I was cycling with M. I've used that up, and because I am all OOP and these meds are very expensive a sweet sweet IF friend of mine donated her left over boxes of bravelle! So a huge THANK YOU to her!! At least I don't have to worry about that expense.

Picking up my meds today and will start popping pills tomorrow night! Bring it on!

Wednesday, May 11, 2011

CD 15

I have to start out by saying that I truly love my RE's office and the staff there. It is all the same staff from the last time I cycled, so I have gotten a chance to really "know" a lot of them and vise vera through the years. My Dr. is amazing and really trying his best to accommodate my OOPness, and they are all just rooting for me. Today they gave me a bag of 8 boxes of Crinone to try and save me a little money and 2 of the nurses were fighting for which one was going to get to do my IUI. I just love all of them! And in case you were wondering about the IUI...well  this thing is just dragging on and on...but I've spent so much time and money already that there is no point in stopping now.

Today's daily vag cam visit showed 3 on the left still at 18, 17, and 15 with a few smaller ones. Still nothing considerable on the right. And my OPK was still negative today. So they did grow. A little.  I knew I should have done a 75 shot yesterday instead of a 50. Me and the Dr went back and forth a little bit about it, but he was still worried because of my age and the fact that I could potentially have too many, so 50 it was even though I was pushing for 75. Well I was right. And I made sure to tell him that today ; )

And just because things cant possibly go the way expected to now (we all thought I would defiantly trigger today), I'm not. Instead I did another shot of Bravelle. 75 units this time. Because sometimes a woman just knows best!

BUT

I can at least say that I am on the books now! I will trigger tomorrow night at 10:30 pm and am scheduled for an IUI on Saturday morning at 8:30 am. There is no reason for me to come in again tomorrow, because even if they don't grow at all (which shouldn't be the case, they should at least grow another 1mm) that 18, 17 and maybe even the 15 should each have a viable mature egg. We are just pushing for a little closer to the "ideal" 20mm.

Me and the RE also had a pretty heart to heart conversation about what he would do if he were in this position, and he thinks because this cycle has gone so array that we should only thaw a MAXIMUM of 3 vials, no matter what the counts and save the rest for a more textbook cycle. I agree, although don't get me wrong this could still result in a pregnancy and he made me very aware of that! I should have 2-3 mature eggs, and although they are all on one side, it is still very possible! I don't have too much hope and would feel better if there were targets on each side, but it is what it is at this point and it is completely out of my hands and into gods.

So now I just PRAY that I don't get a + OPK tomorrow, because if I do my IUI will be pushed to Friday. The 13th. I would just much rather have immaculate timing than surge on my own.

Tuesday, May 10, 2011

CD 14

Annnnnd the saga continues folks. I keep hoping that every time I post an update here that I will have a definite answer of what is going with my cycle, but once again my body has its own ideas. Even my Dr. thinks this whole thing is pretty bizarre! I went in today and low and behold my ovaries look EXACTLY like they did on Sunday! I have a 17, 16, 15, 14, 13, 12, and an 11 on the left side. And only 2 other little guys on the right (10 and 13). Is that bad to have all of them on one side?? That's pretty much how things were looking on Sunday, then I apparently stalled out a little for the last 2 days and now back to where they were. Freaky Freaky! So the extra little shot yesterday must have given them the memo that this isn't over yet.

However, I am still not ready. My RE thought that I should do another shot today and *hopefully* I'll be ready for trigger tomorrow for an IUI on Friday. But because I had already used all of my 300 unit cartridge with this cycle already and he didn't want me busting into a whole new one, he called in a 75 unit vial of Bravelle upstairs to the pharmacy. So I ran upstairs, paid the 55.00 bucks, came back down stairs, mixed the meds and gave myself a shot right there on the spot. Done and Done.

He said I didn't have to come back tomorrow, remember I am all OOP and paying $290 a pop here so he is trying to be mindful of that, which I do appreciate. He said that I could just go ahead and trigger tomorrow night. We discussed this and I told him that I wasn't so sure about how I felt about that. What I have learned over the last 6 days is that I can no longer trust my body to do what it should do. Theoretically, they should have continued to grow over these last couple days. Not stop. And yes, they should grow and be ready tomorrow but after all this, I am not sure that's what will happen. I am just not willing to take ANY chances here and would rather shell out the extra $$ than waste my only shot at ever having another baby. I just cant.

So I'll be shelping my ass back to the RE's office tomorrow once again, for the 4th day in a row and my 5th so far this cycle for another u/s. I really don't mind it, except the money part. Either way, we decided that since this has gotten so crazy that if for any reason I am not ready tomorrow- we are just going to cancel, scrap this cycle, and start over. So much has happened already, that if I am not ready tomorrow I am not prepared to continue on under these weirdo circumstance.


Also, before I forget we all had a suedo meeting while I was there. Myself, my RE, and the sperm guy. I feel bad calling him that, but I don't know what his official job title is. I just wanted to make sure that we were all on the same page as to what we are dealing with and what exactly will go down Friday, if that is IUI day. Sperm guy says he will start with defrosting 2 vials first, then add a 3rd and so on until we hit 5 mil. or above. What he told me next had me spinning into a full blown panic attack. He said that the sperm has not been washed or prepped! WHATS THAT YOU SAY SPERM GUY??!! My jaw literally hit the floor and stayed there for at least 30 seconds. That means there will be even less in each vial after they spin/wash it. I was under the impression that this was all done at collection time and these numbers were post wash, etc.

I don't know guys, I just really beaten up here about this whole thing. I sure hope all this isn't a sign...